Topic 2: Optical Nanosensor Interface

    Attracted by the beauty of fluorescence and its wide application in biological research, we are developing various fluorescent micro/nanosensors for quantitative imaging of cellular processes. With a strong discipline in Analytical Chemistry, we emphasize the goal of quantitative sensing and imaging.
    Our nanosensors are fabricated with amphiphilic block-copolymers that assembled into nanostructures with organic-aqueous interfaces. The phase-transfer and adsorption of biochemical species around the nanoscopic interface could open new doors to a variety of analytical as well as chemical biological tools.
    In addition, our polymeric nanoparticles (nanoparticles, nanospheres, nanoemulsions, nano-droplets, nanoassemblies, etc.) are readily accumulated in endosomes and lysosomes. Therefore, functionalized nanoprobes become very promising in quantitative imaging of biological process related to these organelles, which could be vital to enrich our understanding of nature.